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Structure of 31912-02-4
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Ethyl 2-(2-nitrophenyl)acetate is a bench-stable, moisture-tolerant reagent featuring a nitro-substituted aryl moiety that enables direct functionalization in transition-metal-catalyzed coupling processes. This electron-deficient ester integrates readily into synthetic sequences requiring ortho-activated aromatic systems, offering predictable regioselectivity and compatibility with standard reaction conditions.
Ethyl 2-(2-nitrophenyl)acetate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to biologically relevant heterocyclic scaffolds. Its ortho-nitroaryl group facilitates directed ortho-metalation and participates in reductive cyclizations, while the ester function supports standard transformations including hydrolysis, reduction, and coupling reactions. The compound exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: