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*For research and further manufacturing use only, not for direct human use.
Structure of 320-42-3
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4-Hydroxy-2-(trifluoromethyl)benzonitrile features a trifluoromethyl group enhancing electron-withdrawal and metabolic stability, while the phenolic hydroxyl enables hydrogen bonding and further functionalization. This scaffold integrates readily into bioactive molecules and serves as a key building block in medicinal chemistry.
4-Hydroxy-2-(trifluoromethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles and functionalized aryl scaffolds. The phenolic hydroxyl group facilitates direct derivatization or protection, while the ortho-trifluoromethyl and para-cyano groups offer strong electron-withdrawing character and compatibility with Suzuki-Miyaura and other cross-coupling reactions. Its bench-stable nature and clean purification profile support scalable synthesis and downstream applications in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: