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Structure of 320-94-5
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2-Nitro-4-(trifluoromethyl)benzoic acid was used in preparation of 4-trifluoromethyl anthranilic acid.
2-Nitro-4-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted heterocycles via standard coupling reactions. Its dual electron-withdrawing groups—nitro and trifluoromethyl—enhance electrophilicity for nucleophilic aromatic substitution and facilitate functionalization at the aromatic ring. The carboxylic acid moiety supports direct derivatization or activation for amide and ester formation, offering robust utility in scaffold diversification. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: