tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate

Name: tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate
Brand: ChemScene
Availability: InStock
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CAS No. 320581-09-7
Cat. No. CS-0036089
Purity≥95%
MDL No.MFCD14529625

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate|CS-0036089

Structure of 320581-09-7

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Description

tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate is a bench-stable, moisture-tolerant protecting group for primary amines, featuring a sterically hindered tert-butyl carbamate moiety. This derivative enables selective amine protection in complex molecular architectures, simplifying purification and enhancing compatibility with diverse reaction conditions.

Application

tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate serves as a stable, bench-ready amino protecting group for primary amines, enabling selective N-alkylation and amide bond formation under mild conditions. Its tert-butyl carbamate moiety offers excellent stability during standard synthetic manipulations and can be readily removed with trifluoroacetic acid or other protic acids, facilitating downstream functionalization in peptide and medicinal chemistry workflows.

General Information

CAS No. 320581-09-7
Cat. No. CS-0036089
Purity ≥95%
MDL No. MFCD14529625
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₂₀N₂O₂
Molecular Weight 188.27
Synonym(s) N-(1-amino-2-methylpropan-2-yl)carbamic acid tert-butyl ester
SMILES O=C(OC(C)(C)C)NC(C)(C)CN

Computational Chemistry Data

TPSA 64.35
LogP 1.2484
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Fatty chain compounds

Key Words

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tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate

CAS No. 320581-09-7

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