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Structure of 3209-71-0
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1,2-Oxazole-3-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 3-position, enabling direct incorporation into bioactive molecules. The oxazole ring imparts metabolic stability and enhanced polarity, while the acidic functionality facilitates salt formation and conjugation reactions under mild conditions. This scaffold serves as a privileged motif in medicinal chemistry for targeted protein inhibition and kinase modulation.
1,2-Oxazole-3-carboxylic acid serves as a versatile scaffold for heterocyclic synthesis, enabling direct access to bioactive oxazole derivatives through standard functionalization protocols. Its carboxylic acid group facilitates conjugation and derivatization under mild conditions, while the oxazole ring exhibits robust bench stability and favorable solubility profiles. This compound functions as a key building block in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents, offering high compatibility with common coupling reagents and orthogonal protection strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P301+P310-P330-P501
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Lot numbers can be found on the outside label of a product: