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Structure of 321535-37-9
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2-Bromo-6-iodo-3-methoxypyridine is a halogenated pyridine derivative featuring strategically positioned bromo and iodo substituents flanking a methoxy group. This electronic and steric configuration enables efficient cross-coupling reactions, particularly in palladium-catalyzed transformations. The molecule exhibits robust stability under standard reaction conditions and facilitates the construction of complex heterocyclic architectures with high regiocontrol.
2-Bromo-6-iodo-3-methoxypyridine serves as a versatile dihalogenated pyridine building block for cross-coupling reactions, enabling efficient construction of substituted heterocycles. The bromo and iodo groups exhibit complementary reactivity in Pd-catalyzed coupling processes, allowing sequential functionalization with high regiocontrol. The methoxy group provides moderate electron-donating character and enhances solubility, while the molecule demonstrates good bench stability and ease of purification—ideal for iterative synthetic strategies in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: