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4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine

  • CAS No. 322691-38-3

  • Cat. No. CS-0130652
  • Purity≥97%
  • MDL No.MFCD00665929

*For research and further manufacturing use only, not for direct human use.

4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine|CS-0130652

Structure of 322691-38-3

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General Information

  • CAS No. 322691-38-3
  • Cat. No. CS-0130652
  • Purity ≥97%
  • MDL No. MFCD00665929
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄ClN₅
  • Molecular Weight 227.69
  • Synonym(s) 2-amino-4-chloro-6-(4-methylpiperazin-1-yl)pyrimidine
  • SMILES NC1=NC(N2CCN(C)CC2)=CC(Cl)=N1

Synthesis

  • Route1
    • In-stock
      N-Methylpiperazine|CS-0009394
      109-01-3
    • null|null
      56-05-3
    • ~69%
    • In-stock
      4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine|CS-0130652
      322691-38-3

    References

    • Altenbach, Robert J.; Adair, Ronald M.; Bettencourt, Brian M.; Black, Lawrence A.; Fix-Stenzel, Shannon R.; Gopalakrishnan, Sujatha M.; Hsieh, Gin C.; Liu, Huaqing; Marsh, Kennan C.; McPherson, Michael J.; Milicic, Ivan; Miller, Thomas R.; Vortherms, Timothy A.; Warrior, Usha; Wetter, Jill M.; Wishart, Neil; Witte, David G.; Honore, Prisca; Esbenshade, Timothy A.; Hancock, Arthur A.; Brioni, Jorge D.; Cowart, Marlon D. Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6571 - 6580

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   0.464
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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