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Structure of 3235-67-4
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2-(piperidin-1-yl)acetic acid features a piperidine ring linked via a methylene spacer to a carboxylic acid group, combining basic nitrogen functionality with moderate lipophilicity. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for modulating solubility and target affinity.
2-(Piperidin-1-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through amide bond formation and derivatization at the carboxylic acid terminus. The piperidinyl group provides a basic nitrogen for salt formation and enhanced solubility, while the acetic acid moiety facilitates conjugation in peptide-like architectures. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: