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Structure of 324579-90-0
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4-Cyclopropylthiazol-2-amine features a thiazole core with a cyclopropyl group at the 4-position and an amino substituent at the 2-position, delivering enhanced metabolic stability and tunable basicity. This scaffold integrates readily into kinase inhibitor frameworks and serves as a key building block in medicinal chemistry campaigns targeting purine-binding sites.
4-Cyclopropylthiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of thiazole-based scaffolds with enhanced metabolic stability. Its cyclopropyl substituent imparts favorable steric and electronic properties, while the amine functionality facilitates straightforward derivatization via amidation, alkylation, or coupling reactions. The compound exhibits good bench stability and is compatible with standard reaction conditions, making it a practical choice for the development of API intermediates and targeted small-molecule libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: