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Structure of 325773-65-7
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Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide features a sterically shielded phosphine oxide core that enhances stability and reduces unwanted coordination. The bulky 2,6-diisopropylphenyl groups provide exceptional resistance to oxidation and moisture, enabling reliable use in catalytic systems and as a ligand scaffold under demanding reaction conditions.
Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide serves as a sterically hindered, bench-stable phosphine oxide widely used in palladium-catalyzed cross-coupling reactions. Its bulky aryl groups enhance solubility and reduce oxidation susceptibility, facilitating efficient ligand transfer in Suzuki-Miyaura and Negishi couplings. The molecule functions as a robust precursor to the corresponding phosphine, enabling reliable catalytic activity under mild conditions with excellent functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: