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Structure of 325775-44-8
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tert-Butyl 3-(aminomethyl)azetidine-1-carboxylate is a bench-stable, moisture-tolerant azetidine derivative featuring a pendant primary amine. This scaffold integrates readily into peptide and small-molecule libraries, offering enhanced solubility and metabolic stability. The tert-butyl ester group enables straightforward deprotection under mild acidic conditions, facilitating downstream functionalization in medicinal chemistry workflows.
tert-Butyl 3-(aminomethyl)azetidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to azetidine-containing scaffolds via straightforward deprotection and functionalization. The tert-butyl carbamate group offers excellent bench stability and facilitates purification, while the primary amine at the 3-position supports diverse transformations including alkylation, acylation, and coupling reactions. Its compatibility with standard peptide and heterocycle synthesis protocols makes it a practical choice for constructing bioactive molecules.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: