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Structure of 32605-06-4
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N-Methyl-2-nitropyridin-3-amine features a pyridine ring bearing both a nitro group at the 2-position and a methylamino substituent at the 3-position, creating a distinct electron-deficient heterocyclic scaffold. This configuration enables direct incorporation into C–H functionalization cascades and facilitates transition-metal-catalyzed cross-coupling reactions under mild conditions. The molecule exhibits enhanced solubility in common organic solvents and stability under standard bench protocols.
N-Methyl-2-nitropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds. Its nitro group facilitates reduction to the corresponding amine for further functionalization, while the N-methylpyridyl moiety offers favorable electronic properties and metabolic stability. The compound exhibits good bench stability and compatibility with standard coupling and cyclization reactions, making it suitable for modular synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: