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Structure of 326827-21-8
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3-Amino-5-cyclobutyl-1H-pyrazole features a pyrazole core functionalized with an amino group at the 3-position and a cyclobutyl substituent at the 5-position, delivering enhanced solubility and steric profile. This scaffold integrates readily into bioactive molecules, offering favorable electronic properties for medicinal chemistry applications.
3-Amino-5-cyclobutyl-1H-pyrazole serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its amino group enables facile derivatization via acylation, alkylation, or coupling reactions, while the cyclobutyl substituent imparts conformational rigidity and enhanced lipophilicity. The pyrazole core exhibits good bench stability and compatibility with standard synthetic protocols, facilitating incorporation into diverse scaffolds through established functional group transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: