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Structure of 32999-37-4
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This tetrahydroisoquinolin-8-ol features a fused heterocyclic scaffold with a phenolic hydroxyl group at the 8-position, conferring enhanced solubility and hydrogen-bonding capacity. The saturated ring system imparts metabolic stability and favorable pharmacokinetic properties, making it a valuable scaffold for medicinal chemistry applications involving CNS-targeted therapeutics and alkaloid-based synthesis.
1,2,3,4-Tetrahydroisoquinolin-8-ol serves as a versatile scaffold for medicinal chemistry and natural product synthesis, featuring a readily functionalizable phenolic hydroxyl group and a saturated isoquinoline core. Its stability under standard reaction conditions enables efficient derivatization via etherification, esterification, or metal-catalyzed coupling reactions. The compound functions as a key intermediate in the construction of alkaloid derivatives and exhibits favorable solubility and purification characteristics for high-throughput screening applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: