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CS-W001157 4
Total: USD 88.00

5-Hydroxy-2-methylbenzoic acid

  • CAS No. 578-22-3

  • Cat. No. CS-W007887
  • Purity≥98%
  • MDL No.MFCD09833184
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Hydroxy-2-methylbenzoic acid|CS-W007887

Structure of 578-22-3

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Description

5-Hydroxy-2-methylbenzoic acid features a carboxylic acid group flanked by a hydroxyl and methyl substituent on the aromatic ring, enabling versatile functionalization. This electron-rich scaffold supports direct coupling reactions and serves as a building block in bioactive molecule synthesis. The compound exhibits enhanced solubility in polar solvents and stability under standard bench conditions.

Application

5-Hydroxy-2-methylbenzoic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted structure enables directed functionalization, while the carboxylic acid and phenolic hydroxyl groups offer complementary handles for coupling, derivatization, and metal complexation. The compound exhibits good bench stability and facilitates efficient purification via recrystallization or chromatography, supporting its use in iterative synthesis workflows.

General Information

  • CAS No. 578-22-3
  • Cat. No. CS-W007887
  • Purity ≥98%
  • MDL No. MFCD09833184
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₃
  • Molecular Weight 152.15
  • Synonym(s) 5-Hydroxy-o-toluic Acid
  • SMILES C1=C(C(=CC=C1O)C)C(=O)O

Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.39882
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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