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Structure of 33097-13-1
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4,6-Dichloro-2-(methylthio)pyrimidine-5-carbonitrile features a highly reactive pyrimidine core with dual chlorines at C4 and C6, enabling selective functionalization. The methylthio group enhances nucleophilicity at C2, while the carbonitrile moiety provides a robust handle for downstream coupling. This combination delivers a versatile building block for medicinal chemistry and agrochemical synthesis under standard conditions.
4,6-Dichloro-2-(methylthio)pyrimidine-5-carbonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of pyrimidine-based scaffolds. The dichloro substitution pattern facilitates sequential nucleophilic aromatic substitution, while the methylthio and nitrile groups offer orthogonal reactivity for downstream functionalization. This compound exhibits excellent bench stability and compatibility with standard coupling protocols, making it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2923
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Class : 8 (6.1)
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Packing Group : Ⅲ
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Hazard Statements : H301-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: