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Structure of 33184-48-4
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4-Chloro-2-iodo-1-methylbenzene features a strategically positioned iodine atom enabling efficient cross-coupling reactions, while the chloro and methyl groups provide orthogonal reactivity and steric modulation. This trifunctional aromatic scaffold integrates seamlessly into complex molecular architectures under standard conditions.
4-Chloro-2-iodo-1-methylbenzene serves as a versatile biaryl building block in cross-coupling chemistry, enabling efficient Pd-catalyzed transformations such as Suzuki-Miyaura and Stille reactions. The ortho-iodo group exhibits high reactivity, while the meta-chloro and para-methyl substituents provide orthogonal functionalization potential and enhanced stability under standard reaction conditions. This compound facilitates the construction of complex substituted arenes with predictable regiochemistry and is well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: