Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Nitro-4-pyridinecarboxylic acid

  • CAS No. 33225-74-0

  • Cat. No. CS-W017820
  • Purity≥98%
  • MDL No.MFCD04114160

*For research and further manufacturing use only, not for direct human use.

2-Nitro-4-pyridinecarboxylic acid|CS-W017820

Structure of 33225-74-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 33225-74-0
  • Cat. No. CS-W017820
  • Purity ≥98%
  • MDL No. MFCD04114160
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄N₂O₄
  • Molecular Weight 168.11
  • Synonym(s) 2-nitropyridine-4-carboxylic Acid
  • SMILES O=C(C1=CC([N+]([O-])=O)=NC=C1)O

Description

2-Nitro-4-pyridinecarboxylic acid features a pyridine ring bearing both a nitro group at the 2-position and a carboxylic acid at the 4-position, creating a strongly electron-deficient heteroaromatic scaffold. This dual functionality enables direct incorporation into coupling reactions, metal coordination complexes, and bioactive molecule synthesis. The compound exhibits enhanced solubility in polar solvents and stability under standard bench conditions.

Application

2-Nitro-4-pyridinecarboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its pyridine core enables metal-catalyzed coupling reactions, while the ortho-nitro and carboxylic acid groups provide orthogonal reactivity for functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step syntheses of API candidates and advanced ligands.

Synthesis

  • Route1
    • 4-Methyl-2-nitropyridine|CS-0153153
      18368-71-3
    • ~%
    • In-stock
      2-Nitro-4-pyridinecarboxylic acid|CS-W017820
      33225-74-0

    References

    • Journal of the American Chemical Society, , vol. 76, p. 3167

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   93.33
  • LogP   0.688
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Nitro-4-pyridinecarboxylic acid sigma2-Nitro-4-pyridinecarboxylic acid manufacturer2-Nitro-4-pyridinecarboxylic acid price2-Nitro-4-pyridinecarboxylic acid structure2-Nitro-4-pyridinecarboxylic acid SDSbuy 2-Nitro-4-pyridinecarboxylic acid2-Nitro-4-pyridinecarboxylic acid supplier2-Nitro-4-pyridinecarboxylic acid uses2-Nitro-4-pyridinecarboxylic acid molecular weightprice of 2-Nitro-4-pyridinecarboxylic acid2-Nitro-4-pyridinecarboxylic acid chemical name formula of 2-Nitro-4-pyridinecarboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label