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Structure of 7396-44-3
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Benzyl 2-(diethoxyphosphoryl)acetate delivers a reactive phosphonate handle for C–C bond formation, featuring a bench-stable diethoxyphosphoryl group flanked by a benzyloxy acetyl scaffold. This configuration enables efficient coupling in Negishi and Suzuki-Miyaura protocols, with enhanced tolerance to moisture and air during standard synthetic workflows.
Benzyl 2-(diethoxyphosphoryl)acetate serves as a versatile synthon in carbonyl-alkylation and phosphorylation reactions, enabling efficient access to β-keto phosphonates under mild conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward purification and integration into multi-step sequences. The molecule functions as a key building block for heterocyclic scaffolds and bioactive compound synthesis, particularly in the development of kinase inhibitors and phosphonate-containing analogs.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: