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Structure of 33225-74-0
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2-Nitro-4-pyridinecarboxylic acid features a pyridine ring bearing both a nitro group at the 2-position and a carboxylic acid at the 4-position, creating a strongly electron-deficient heteroaromatic scaffold. This dual functionality enables direct incorporation into coupling reactions, metal coordination complexes, and bioactive molecule synthesis. The compound exhibits enhanced solubility in polar solvents and stability under standard bench conditions.
2-Nitro-4-pyridinecarboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its pyridine core enables metal-catalyzed coupling reactions, while the ortho-nitro and carboxylic acid groups provide orthogonal reactivity for functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step syntheses of API candidates and advanced ligands.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: