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CS-W001157 4
Total: USD 88.00

2-Chloro-4-cyanopyridine

  • CAS No. 33252-30-1

  • Cat. No. CS-D0766
  • Molecule weight138.55
  • Purity≥96%
  • MDL No.MFCD00174318

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4-cyanopyridine|CS-D0766

Structure of 33252-30-1

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General Information

  • CAS No. 33252-30-1
  • Cat. No. CS-D0766
  • Purity ≥96%
  • MDL No. MFCD00174318
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClN₂
  • Molecular Weight 138.55
  • Synonym(s) 2-Chloro-Isonicotinonitrile
  • SMILES N#CC1=CC(Cl)=NC=C1

Description

2-Chloro-4-cyanopyridine is a versatile heterocyclic building block featuring a chlorine substituent at the 2-position and a cyano group at the 4-position on the pyridine ring. This combination enables selective functionalization in cross-coupling reactions and facilitates the synthesis of advanced pharmaceutical intermediates and agrochemical scaffolds under standard conditions.

Synthesis

  • Route1
    • null|null
      14906-59-3
    • In-stock
      Carbon|CS-0021794
      7440-44-0
    • ~%
    • In-stock
      2-Chloro-4-cyanopyridine|CS-D0766
      33252-30-1

    References

    • US2003/55255 A1, ;
  • Route2
    • null|null
      14906-59-3
    • ~71%
    • In-stock
      2-Chloro-4-cyanopyridine|CS-D0766
      33252-30-1

    References

    • Frey, Lisa F; Marcantonio, Karen; Frantz, Doug E; Murry, Jerry A; Tillyer, Richard D; Grabowski, Edward J.J; Reider, Paul J Tetrahedron Letters, 2001 , vol. 42, # 39 p. 6815 - 6818
  • Route3
    • null|null
      14906-59-3
    • null|null
      10026-13-8
    • ~23%
    • In-stock
      2-Chloro-4-cyanopyridine|CS-D0766
      33252-30-1

    References

    • Sterling Winthrop Inc. Patent: US5294612 A1, 1994 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.68
  • LogP   1.60668
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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