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CS-W001157 4
Total: USD 88.00

2,6-Dichloroisonicotinonitrile

  • CAS No. 32710-65-9

  • Cat. No. CS-W001246
  • Purity≥98%
  • MDL No.MFCD00173784
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloroisonicotinonitrile|CS-W001246

Structure of 32710-65-9

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Description

2,6-Dichloroisonicotinonitrile features a rigid pyridine core bearing electron-withdrawing chlorine substituents at the 2 and 6 positions and a nitrile group at the 3 position. This configuration imparts high electrophilicity and stability under standard conditions, enabling its use in coupling reactions and as a building block for heterocyclic synthesis.

Application

2,6-Dichloroisonicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted pyridine scaffolds via nucleophilic aromatic substitution. Its dual chloro groups facilitate sequential functionalization, while the nitrile moiety offers compatibility with standard transformations such as hydrolysis or reduction. Bench-stable and readily purified, it functions effectively in multi-step syntheses requiring precise regiocontrol and functional group tolerance.

General Information

  • CAS No. 32710-65-9
  • Cat. No. CS-W001246
  • Purity ≥98%
  • MDL No. MFCD00173784
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₂N₂
  • Molecular Weight 173.00
  • Synonym(s) 4-Pyridinecarbonitrile, 2,6-dichloro-
  • SMILES N#Cc1cc(Cl)nc(c1)Cl

Computational Chemistry Data

  • TPSA   36.68
  • LogP   2.26008
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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