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Structure of 33263-43-3
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4-Chloropyridine-3-sulfonamide features a pyridine ring bearing both chloro and sulfonamide substituents at meta positions, enabling strong hydrogen bonding and enhanced solubility. This combination imparts stability and facilitates integration into bioactive scaffolds for medicinal chemistry applications.
4-Chloropyridine-3-sulfonamide serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. Its chlorine atom at the 4-position provides a reliable handle for C–X bond formation, while the sulfonamide group offers hydrogen-bonding capability and metabolic stability. The compound exhibits good bench stability and compatibility with diverse reaction conditions, facilitating efficient synthesis of bioactive molecules and functional intermediates in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: