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Structure of 332903-47-6
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2-Chloro-4-fluoro-6-methylaniline features a trifluorinated aryl scaffold with strategically positioned electron-withdrawing chlorine and fluorine substituents, paired with a methyl group at the para position. This combination imparts enhanced metabolic stability and targeted electronic modulation, enabling efficient incorporation into pharmaceutical intermediates and functionalized heterocycles under standard bench conditions.
2-Chloro-4-fluoro-6-methylaniline serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its ortho-chloro and meta-fluoro substituents provide enhanced regioselectivity in coupling reactions, while the methyl group offers steric and electronic modulation. The compound exhibits good bench stability and facilitates efficient downstream functionalization via palladium-catalyzed cross-coupling, amide formation, and electrophilic substitution.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: