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CS-W001157 4
Total: USD 88.00

3,5-Dichloro-4-hydroxybenzoic acid

  • CAS No. 3336-41-2

  • Cat. No. CS-W005243
  • Purity≥98%
  • MDL No.MFCD00002550

*For research and further manufacturing use only, not for direct human use.

3,5-Dichloro-4-hydroxybenzoic acid|CS-W005243

Structure of 3336-41-2

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General Information

  • CAS No. 3336-41-2
  • Cat. No. CS-W005243
  • Purity ≥98%
  • MDL No. MFCD00002550
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄Cl₂O₃
  • Molecular Weight 207.01
  • Synonym(s) 4-Hydroxy-3,5-Dichloro Benzoic Acid
  • SMILES OC(=O)C1=CC(Cl)=C(O)C(Cl)=C1

Description

3,5-Dichloro-4-hydroxybenzoic acid features a highly electron-deficient aromatic core flanked by two chlorine substituents and a phenolic hydroxyl group, enabling robust conjugation in synthetic transformations. This bench-stable derivative integrates readily into pharmaceutical intermediates and functionalized polymers under standard conditions.

Application

3,5-Dichloro-4-hydroxybenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering predictable reactivity at both the carboxylic acid and phenolic hydroxyl groups. Its ortho-chlorinated aromatic framework provides enhanced metabolic stability and facilitates downstream functionalization via standard coupling reactions. The compound exhibits good bench stability and is amenable to purification by recrystallization or column chromatography, enabling reliable use in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   2.3972
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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