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Structure of 334-22-5
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Bis(2-chloroethyl)amine is a bifunctional alkylating agent featuring two reactive chloroethyl groups. This compound readily forms covalent cross-links with nucleophilic sites in biomolecules, enabling targeted conjugation in synthetic and biochemical applications. The molecule's high reactivity under mild conditions facilitates efficient derivatization of proteins, nucleic acids, and other functionalized substrates.
Bis(2-chloroethyl)amine serves as a versatile bifunctional electrophile in synthetic organic chemistry, enabling efficient intramolecular cyclization to form aziridine rings under mild conditions. Its two reactive chloroethyl groups facilitate rapid alkylation of nucleophiles, making it valuable for the construction of nitrogen-containing heterocycles and as a building block in peptide conjugation strategies. The compound exhibits good bench stability and is compatible with a range of functional groups, supporting its use in iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: