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Structure of 33512-26-4
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Diethyl (phthalimidomethyl)phosphonate features a phosphonate group tethered to a phthalimide-bearing methylene linker, enabling direct incorporation into heterocyclic scaffolds. This stable, moisture-tolerant reagent facilitates efficient P–C bond formation in synthetic sequences requiring nitrogen-anchored phosphonates.
Diethyl (phthalimidomethyl)phosphonate serves as a versatile synthon for the construction of phosphonate-containing heterocycles and bioactive scaffolds. Its phthalimide-protected amine moiety enables selective deprotection and functionalization, while the phosphonate group facilitates C–C bond formation via Horner–Wadsworth–Emmons or related olefination reactions. The compound exhibits excellent bench stability, ease of handling, and compatibility with common protecting group strategies, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: