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Structure of 337362-21-7
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Methyl 5-cyano-2-fluorobenzoate features a strategically positioned cyano group and fluorine atom on the aromatic ring, enhancing electron deficiency and metabolic stability. This combination enables efficient incorporation into complex heterocycles and facilitates transition metal-catalyzed coupling reactions under standard conditions.
Methyl 5-cyano-2-fluorobenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocycles and bioactive scaffolds. Its orthogonal functionality—cyano, fluoro, and ester groups—facilitates sequential transformations via nucleophilic substitution, coupling reactions, and cyclization protocols. Bench-stable and amenable to purification by flash chromatography or recrystallization, it supports scalable synthesis in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: