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Structure of 340006-71-5
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2-Cyclopropylpyridin-4-amine features a pyridine core with a cyclopropyl group at the 2-position and an amino substituent at the 4-position, delivering enhanced metabolic stability and improved solubility. This scaffold integrates readily into kinase inhibitors and bioactive molecules, offering favorable binding affinity in target-directed drug discovery.
2-Cyclopropylpyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its pyridine core offers favorable electronic properties and metabolic stability, while the cyclopropyl group enhances lipophilicity and conformational rigidity. The primary amine facilitates facile derivatization via acylation, alkylation, or transition-metal-catalyzed cross-coupling, supporting rapid SAR exploration. Bench-stable and readily purified by chromatography or recrystallization, it functions effectively in both small-molecule synthesis and API development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: