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Structure of 3401-47-6
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1-Bromo-2-methoxynaphthalene features a bromine atom at the 1-position and a methoxy group at the 2-position of the naphthalene core. This substitution pattern creates a polarized, electron-deficient aromatic system ideal for palladium-catalyzed cross-coupling reactions. The methoxy group enhances solubility while maintaining stability under standard reaction conditions.
1-Bromo-2-methoxynaphthalene serves as a versatile building block in Suzuki-Miyaura and Negishi coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The methoxy group enhances solubility and modulates electronic properties, while the bromine substituent offers high reactivity and compatibility with palladium-catalyzed transformations. Bench-stable and readily purified by column chromatography, it functions reliably in the synthesis of functionalized naphthalene derivatives for pharmaceutical and materials applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: