3-Bromo-7-chloroimidazo[1,2-a]pyridine

Name: 3-Bromo-7-chloroimidazo[1,2-a]pyridine
Brand: ChemScene
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CAS No. 342613-67-6
Cat. No. CS-0036470
Purity≥97%
MDL No.MFCD11111834

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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3-Bromo-7-chloroimidazo[1,2-a]pyridine|CS-0036470

Structure of 342613-67-6

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Description

3-Bromo-7-chloroimidazo[1,2-a]pyridine is a heterocyclic scaffold featuring complementary halogen substituents at positions 3 and 7. This electron-deficient core enables direct coupling in cross-coupling reactions and facilitates integration into bioactive molecules. The molecule exhibits robust stability under standard reaction conditions and serves as a key intermediate in medicinal chemistry and materials science applications.

Application

3-Bromo-7-chloroimidazo[1,2-a]pyridine serves as a versatile building block for constructing bioactive heterocycles in medicinal chemistry. The molecule enables palladium-catalyzed cross-coupling reactions due to its bromo substituent, while the chloro group offers orthogonal reactivity. Its stability under standard synthetic conditions and compatibility with diverse functional groups facilitate efficient assembly of complex scaffolds, making it valuable for drug discovery campaigns requiring modular imidazopyridine frameworks.

General Information

CAS No. 342613-67-6
Cat. No. CS-0036470
Purity ≥97%
MDL No. MFCD11111834
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrClN₂
Molecular Weight 231.48
Synonym(s) 3-BROMO-7-CHLOROIMIDAZO [1,2-A]PYRIDINE
SMILES C1=CN2C(=CN=C2C=C1Cl)Br

Computational Chemistry Data

TPSA 17.3
LogP 2.7502
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Key Words

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3-Bromo-7-chloroimidazo[1,2-a]pyridine

CAS No. 342613-67-6

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