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Structure of 342636-66-2
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3,5-Dimethyl-4-fluorophenylboronic acid features a sterically hindered aryl boronate with enhanced stability and predictable coupling efficiency. The para-fluoro substituent improves reactivity in Suzuki-Miyaura cross-coupling reactions, while the ortho-dimethyl groups provide steric protection against protodeboronation. This bench-stable reagent facilitates reliable carbon-carbon bond formation under standard conditions.
3,5-Dimethyl-4-fluorophenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient carbon-carbon bond formation under mild conditions. Its fluorinated aryl boronic acid structure offers enhanced stability and compatibility with diverse functional groups, facilitating the synthesis of complex biaryl scaffolds relevant to pharmaceutical and agrochemical research. The ortho-methyl substituents provide steric control and improve bench stability, while the para-fluoro group enables further derivatization through nucleophilic aromatic substitution.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P403-P405-P501
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Lot numbers can be found on the outside label of a product: