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CS-W001157 4
Total: USD 88.00

1,2,5-Trichloro-3-nitrobenzene

  • CAS No. 34283-94-8

  • Cat. No. CS-0168030
  • Purity≥98%
  • MDL No.MFCD00456797
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,2,5-Trichloro-3-nitrobenzene|CS-0168030

Structure of 34283-94-8

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Description

1,2,5-Trichloro-3-nitrobenzene features a highly electron-deficient aromatic core stabilized by three chlorine substituents and a nitro group at the 3-position. This configuration enables direct electrophilic substitution reactions under mild conditions, facilitating rapid incorporation into complex molecular architectures. The compound exhibits excellent bench stability and tolerance to moisture, streamlining its use in multi-step syntheses.

Application

1,2,5-Trichloro-3-nitrobenzene serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of complex heterocycles and functionalized aromatic systems. Its three chlorine atoms provide orthogonal sites for palladium-catalyzed cross-coupling reactions, while the nitro group facilitates selective reduction and subsequent derivatization. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 34283-94-8
  • Cat. No. CS-0168030
  • Purity ≥98%
  • MDL No. MFCD00456797
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₃NO₂
  • Molecular Weight 226.44
  • Synonym(s) 2,3,5-Trichloronitrobenzene
  • SMILES O=[N+](C1=C(Cl)C(Cl)=CC(Cl)=C1)[O-]

Computational Chemistry Data

  • TPSA   43.14
  • LogP   3.555
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group :
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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