2-Amino-3,5-dibromopyridine

Name: 2-Amino-3,5-dibromopyridine
Brand: ChemScene
Availability: InStock
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CAS No. 35486-42-1
Cat. No. CS-W002171
Purity≥96%
MDL No.MFCD00038041

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 35486-42-1

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Description

2-Amino-3,5-dibromopyridine features a pyridine core substituted with amino and bromine groups at the 2 and 3,5 positions, respectively. This electron-deficient heterocycle serves as a key building block in the synthesis of functionalized pharmaceutical intermediates and advanced materials. The presence of two bromine atoms enables efficient cross-coupling reactions, while the amino group offers a handle for further derivatization under mild conditions. The compound exhibits good stability under standard handling protocols.

Application

2-Amino-3,5-dibromopyridine serves as a versatile building block for the synthesis of brominated heterocycles and pharmaceutical intermediates. Its dual bromo groups enable palladium-catalyzed cross-coupling reactions, while the amino functionality offers site-specific derivatization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

General Information

CAS No. 35486-42-1
Cat. No. CS-W002171
Purity ≥96%
MDL No. MFCD00038041
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄Br₂N₂
Molecular Weight 251.91
Synonym(s) Maybridge1_001693
SMILES BrC(C=N1)=CC(Br)=C1N

Computational Chemistry Data

TPSA 38.91
LogP 2.1888
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Amino-3,5-dibromopyridine

CAS No. 35486-42-1

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