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CS-W001157 4
Total: USD 88.00

Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate

  • CAS No. 343-67-9

  • Cat. No. CS-0041701
  • Purity≥97%
  • MDL No.MFCD01571344

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate|CS-0041701

Structure of 343-67-9

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General Information

  • CAS No. 343-67-9
  • Cat. No. CS-0041701
  • Purity ≥97%
  • MDL No. MFCD01571344
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇F₃N₂O₃
  • Molecular Weight 236.15
  • Synonym(s) 5-pyrimidinecarboxylic acid, 4-hydroxy-2-(trifluoromethyl)-, ethyl ester
  • SMILES O=C(C1=CN=C(C(F)(F)F)N=C1O)OCC

Synthesis

  • Route1

    References

    • Signal Pharmaceuticals, Inc. Patent: US5935966 A1, 1999 ;
  • Route2
    • null|null
      7732-18-5
    • null|null
      354-37-0
    • In-stock
      Diethyl 2-(ethoxymethylene)malonate|CS-0019402
      87-13-8
    • ~49%
    • Ethyl 4-hydroxy-2-(trifluoromethyl)pyrimidine-5-carboxylate|CS-0041701
      343-67-9

    References

    • Signal Pharmaceuticals, Inc. Patent: US5811428 A1, 1998 ;
  • Route3

    References

    • Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.31
  • LogP   1.3777
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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