2-Bromo-3-methylpyridine

Name: 2-Bromo-3-methylpyridine
Brand: ChemScene
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CAS No. 3430-17-9
Cat. No. CS-W007712
Purity≥97%
MDL No.MFCD00239380

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 3430-17-9

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Description

2-Bromo-3-methylpyridine features a bromine atom at the 2-position and a methyl group at the 3-position on a pyridine ring, creating a sterically hindered, electron-deficient heterocycle. This combination enables selective cross-coupling reactions under palladium catalysis, delivering functionalized pyridyl scaffolds with high regiocontrol. The molecule exhibits bench-stable handling characteristics and compatibility with diverse reaction conditions in medicinal chemistry and materials synthesis.

Application

2-Bromo-3-methylpyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the bromine site. The methyl group provides a handle for further functionalization, while the pyridine core offers favorable electronic properties for subsequent derivatization. Its bench-stable nature and compatibility with standard reaction conditions make it suitable for iterative synthesis of complex pharmaceutical intermediates and agrochemical scaffolds.

General Information

CAS No. 3430-17-9
Cat. No. CS-W007712
Purity ≥97%
MDL No. MFCD00239380
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆BrN
Molecular Weight 172.03
Synonym(s) 2-Bromo-3-picoline
SMILES CC1=CC=CN=C1Br

Computational Chemistry Data

TPSA 12.89
LogP 2.15252
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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2-Bromo-3-methylpyridine

CAS No. 3430-17-9

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