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Structure of 3430-18-0
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2,5-Dibromo-3-methylpyridine features a pyridine core substituted with bromine atoms at the 2- and 5-positions and a methyl group at the 3-position, delivering a sterically accessible, electron-deficient platform. This configuration enables direct coupling in cross-coupling reactions, particularly in palladium-catalyzed processes, where the halogen sites facilitate selective functionalization. The molecule exhibits bench-stable handling characteristics under standard conditions.
2,5-Dibromo-3-methylpyridine serves as a versatile building block for constructing functionalized heterocycles in medicinal chemistry and materials science. The methyl group enables directed ortho-metalation, while the dibromo substitution pattern facilitates sequential cross-coupling reactions under palladium catalysis. Its bench-stable solid form and compatibility with standard Suzuki, Stille, and Negishi protocols make it ideal for iterative synthesis of complex pyridyl scaffolds.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: