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Structure of 1272758-17-4
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tert-Butyl 8-oxo-2-azaspiro[4.5]decane-2-carboxylate is a sterically shielded spirocyclic lactam precursor featuring a bench-stable ketone at the C8 position and a protected carboxylic acid ester. This configuration enables direct functionalization at the azaspiro scaffold, facilitating access to complex nitrogen-containing heterocycles in medicinal chemistry campaigns.
tert-Butyl 8-oxo-2-azaspiro[4.5]decane-2-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry, enabling efficient access to complex nitrogen-containing frameworks. The molecule features a ketone at C8 and a protected carboxylic acid at C2, both of which are amenable to selective transformations. Its robust tert-butyl ester facilitates straightforward deprotection under mild acidic conditions, while the spirocyclic core provides defined stereochemistry and rigidity advantageous in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: