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Structure of 34352-59-5
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1-Methylpiperazine dihydrochloride offers a highly soluble, bench-stable platform for medicinal chemistry and process development. The protonated piperazine core delivers strong nucleophilicity and enhanced solubility in aqueous and polar organic media. This salt form improves handling and storage stability while maintaining reactivity for amine coupling, macrocyclization, and bioconjugation applications.
1-Methylpiperazine dihydrochloride serves as a versatile nitrogen source in medicinal chemistry, enabling efficient construction of piperazine-based scaffolds. Its crystalline form ensures excellent bench stability and ease of handling, while the protonated amine groups facilitate salt formation for improved solubility and purification. The compound reacts reliably with acyl chlorides, sulfonyl chlorides, and epoxides, supporting diverse functionalization in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: