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CS-W001157 4
Total: USD 88.00

1-Methylpiperazine dihydrochloride

  • CAS No. 34352-59-5

  • Cat. No. CS-W017563
  • Purity≥97%
  • MDL No.MFCD00012755
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Methylpiperazine dihydrochloride|CS-W017563

Structure of 34352-59-5

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Description

1-Methylpiperazine dihydrochloride offers a highly soluble, bench-stable platform for medicinal chemistry and process development. The protonated piperazine core delivers strong nucleophilicity and enhanced solubility in aqueous and polar organic media. This salt form improves handling and storage stability while maintaining reactivity for amine coupling, macrocyclization, and bioconjugation applications.

Application

1-Methylpiperazine dihydrochloride serves as a versatile nitrogen source in medicinal chemistry, enabling efficient construction of piperazine-based scaffolds. Its crystalline form ensures excellent bench stability and ease of handling, while the protonated amine groups facilitate salt formation for improved solubility and purification. The compound reacts reliably with acyl chlorides, sulfonyl chlorides, and epoxides, supporting diverse functionalization in API development workflows.

General Information

  • CAS No. 34352-59-5
  • Cat. No. CS-W017563
  • Purity ≥97%
  • MDL No. MFCD00012755
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₄Cl₂N₂
  • Molecular Weight 173.08
  • Synonym(s) 1-MethylpiperazineDihydrochloride
  • SMILES CN1CCNCC1.[H]Cl.[H]Cl

Computational Chemistry Data

  • TPSA   15.27
  • LogP   0.365
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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