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Structure of 343781-36-2
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2,4-Dichloro-3-iodopyridine offers a strategically positioned iodine atom on a chlorinated pyridine scaffold, enabling direct coupling in cross-coupling reactions. The electron-deficient heterocycle facilitates palladium-catalyzed transformations, while the orthogonal halogen pattern supports sequential functionalization. This bench-stable reagent integrates efficiently into complex molecule synthesis workflows.
2,4-Dichloro-3-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted pyridines via palladium-catalyzed reactions. The iodo group facilitates Suzuki, Stille, and Negishi couplings, while the dichloro substituents offer orthogonal reactivity for further functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for iterative synthesis of complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: