2,4-Dichloro-5-iodopyridine

Name: 2,4-Dichloro-5-iodopyridine
Brand: ChemScene
Availability: InStock
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CAS No. 343781-49-7
Cat. No. CS-W021506
Purity≥98%
MDL No.MFCD09033755

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 343781-49-7

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Description

2,4-Dichloro-5-iodopyridine is a halogenated pyridine derivative featuring complementary reactive sites for cross-coupling and functionalization. The electron-deficient ring facilitates palladium-catalyzed reactions, while the iodine moiety enables selective C–C bond formation. This compound serves as a key building block in medicinal chemistry and agrochemical synthesis, offering high reactivity under mild conditions.

Application

2,4-Dichloro-5-iodopyridine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The iodine moiety facilitates efficient Suzuki, Stille, or Negishi couplings, while the dichloro substitution pattern allows for selective functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for constructing complex pyridine-based scaffolds in API development and materials science applications.

General Information

CAS No. 343781-49-7
Cat. No. CS-W021506
Purity ≥98%
MDL No. MFCD09033755
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂Cl₂IN
Molecular Weight None
Synonym(s) Pyridine, 2,4-dichloro-5-iodo-
SMILES IC1=CN=C(Cl)C=C1Cl

Computational Chemistry Data

TPSA 12.89
LogP 2.993
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,4-Dichloro-5-iodopyridine

CAS No. 343781-49-7

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