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Structure of 97966-01-3
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2,3-Dichloro-5-iodopyridine is a halogenated pyridine derivative featuring complementary reactivity at the 2-, 3-, and 5-positions. This electron-deficient heterocycle enables direct cross-coupling transformations under palladium catalysis, serving as a key building block for functionalized pharmaceutical intermediates and agrochemical scaffolds. The strategic placement of chlorine and iodine atoms facilitates sequential derivatization while maintaining stability under standard reaction conditions.
2,3-Dichloro-5-iodopyridine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The iodine moiety facilitates efficient C–C and C–heteroatom bond formation, while the dichloro substituents provide structural rigidity and tune electronic properties. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for constructing complex pyridine-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: