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CS-W001157 4
Total: USD 88.00

4-(Dimethylamino)benzylamine dihydrochloride

  • CAS No. 34403-52-6

  • Cat. No. CS-W014709
  • Purity≥97%
  • MDL No.MFCD00012862

*For research and further manufacturing use only, not for direct human use.

4-(Dimethylamino)benzylamine dihydrochloride|CS-W014709

Structure of 34403-52-6

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General Information

  • CAS No. 34403-52-6
  • Cat. No. CS-W014709
  • Purity ≥97%
  • MDL No. MFCD00012862
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆Cl₂N₂
  • Molecular Weight 223.14
  • Synonym(s) 4-(aMinoMethyl)-N,N-diMethylaniline dihydrochloride
  • SMILES CN(C1=CC=C(CN)C=C1)C.Cl.Cl

Description

4-(Dimethylamino)benzylamine dihydrochloride features a tertiary amine-bearing aromatic side chain, delivering enhanced solubility and nucleophilicity in aqueous or polar organic media. This salt form ensures stability and ease of handling during synthesis workflows. The para-dimethylamino group imparts strong electron-donating character, making it effective for coupling reactions and as a building block in bioconjugation.

Application

4-(Dimethylamino)benzylamine dihydrochloride serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of target molecules through its amine functionality and electron-rich aromatic core. The dihydrochloride salt enhances solubility and stability in aqueous and polar organic media, facilitating straightforward handling and purification. It functions effectively in amide coupling, reductive amination, and heterocycle formation, commonly employed in the construction of kinase inhibitors and CNS-targeted scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   2.0549
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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