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Structure of 345642-86-6
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5-Hydroxypyrimidine-2-carbonitrile features a hydroxyl group at the 5-position and a nitrile moiety at the 2-position, enabling dual functionalization in synthetic sequences. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and bioactive scaffolds, offering enhanced solubility and stability under standard conditions.
5-Hydroxypyrimidine-2-carbonitrile serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds through nucleophilic substitution and cyclization reactions. Its hydroxyl and nitrile groups offer orthogonal reactivity for functionalization, while the compound exhibits sufficient bench stability for routine handling. This dual functionality facilitates integration into medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents, particularly where pyrimidine cores are required.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: