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Structure of 34743-49-2
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4-Methoxy-2,6-dimethylaniline features a methoxy group at the para position and two methyl substituents flanking the amino nitrogen, delivering enhanced electron density and steric protection. This combination imparts improved stability and solubility in organic solvents, facilitating use in coupling reactions and as a building block for functional dyes and pharmaceutical intermediates.
4-Methoxy-2,6-dimethylaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced solubility and metabolic stability compared to unsubstituted anilines. Its ortho-methyl groups provide steric shielding, improving bench stability and reducing undesired side reactions. The molecule functions effectively in Pd-catalyzed cross-coupling reactions and serves as a key intermediate for heterocyclic scaffolds, particularly in the construction of substituted pyridines and benzimidazoles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: