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Structure of 34896-80-5
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1-Bromo-3-(methylsulfonyl)benzene features a bromine atom flanked by a methylsulfonyl group, enabling selective cross-coupling reactions. This electron-deficient aryl halide exhibits enhanced stability and solubility in polar solvents, facilitating efficient Pd-catalyzed transformations. The sulfone moiety improves functional group tolerance and streamlines purification workflows in synthetic sequences.
1-Bromo-3-(methylsulfonyl)benzene serves as a versatile aryl halide building block for palladium-catalyzed cross-coupling reactions, including Suzuki, Stille, and Negishi couplings. The methylsulfonyl group enhances solubility and provides orthogonal reactivity in multi-step syntheses. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for constructing complex pharmaceutical intermediates and heterocyclic scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: