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Structure of 6296-99-7
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Diethyl 2-(aminomethylene)malonate features a reactive aminomethylene group flanked by two ester functionalities, enabling direct incorporation into heterocyclic scaffolds. This versatile diester serves as a key building block for synthesizing pyrrolidine and piperidine derivatives under mild conditions. The molecule exhibits enhanced stability compared to analogous malonate precursors, facilitating handling in standard laboratory workflows.
Diethyl 2-(aminomethylene)malonate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrrolidine and imidazole scaffolds via condensation and cyclization reactions. Its dual ester functionality and readily available enolizable α-amino carbonyl group facilitate robust transformations under mild conditions, offering excellent functional group tolerance and bench stability for scalable applications in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: