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Structure of 34941-90-7
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2,4-Difluoropyridine is a fluorinated heterocycle featuring two strategically positioned fluorine atoms that enhance electrophilicity at the C2 and C4 positions. This electron-deficient pyridine derivative serves as a key scaffold in medicinal chemistry, enabling efficient coupling reactions and facilitating metabolic stability in bioactive molecules.
2,4-Difluoropyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at C3 via nucleophilic substitution due to the ortho/para directing effect of fluorine. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient access to diverse heterocyclic scaffolds. The molecule functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive compounds, offering predictable regioselectivity and excellent functional group tolerance in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
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Lot numbers can be found on the outside label of a product: