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CS-W001157 4
Total: USD 88.00

3-Fluoro-4-hydroxybenzoic acid

  • CAS No. 350-29-8

  • Cat. No. CS-W008917
  • Purity≥98%
  • MDL No.MFCD00143161

*For research and further manufacturing use only, not for direct human use.

3-Fluoro-4-hydroxybenzoic acid|CS-W008917

Structure of 350-29-8

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General Information

  • CAS No. 350-29-8
  • Cat. No. CS-W008917
  • Purity ≥98%
  • MDL No. MFCD00143161
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅FO₃
  • Molecular Weight 156.11
  • Synonym(s) 4-Hydroxy-3-fluorobenzoic acid; 5-Fluoro-4-hydroxybenzoic acid; 4-Carboxy-2-fluorophenol
  • SMILES O=C(O)C1=CC=C(O)C(F)=C1

Description

3-Fluoro-4-hydroxybenzoic acid features a strategically positioned fluorine atom and hydroxyl group on the aromatic ring, enabling enhanced electronic modulation and hydrogen bonding capacity. This combination supports efficient conjugation in bioactive molecule synthesis and facilitates solubility in polar reaction media. The compound serves as a key scaffold for pharmaceutical intermediates and functional materials.

Synthesis

  • Route1

    References

    • Svensson, Anette; Fex, Tomas; Kihlberg, Jan Tetrahedron Letters, 1996 , vol. 37, # 42 p. 7649 - 7652
  • Route2
    • null|null
      15719-64-9
    • ~%
    • In-stock
      3-Fluoro-4-hydroxybenzoic acid|CS-W008917
      350-29-8
    • In-stock
      3-Fluoro-2-hydroxybenzoic acid|CS-W016244
      341-27-5

    References

    • Journal of the American Chemical Society, , vol. 68, p. 2502
  • Route3
    • In-stock
      Baroxavir impurity 17|CS-0067533
      85118-04-3
    • ~17%
    • 3-Fluoro-4-hydroxybenzamide|CS-0687667
      1155354-10-1
    • In-stock
      3-Fluoro-4-hydroxybenzoic acid|CS-W008917
      350-29-8

    References

    • Synlett, , # 4 p. 633 - 637

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335-H411
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.2295
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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